Direct Synthesis of Alkenyl Boronic Esters from Unfunctionalized Alkenes: A Boryl-Heck Reaction - Journal of the American Chemical Society (ACS Publications)

Direct Synthesis of Alkenyl Boronic Esters from Unfunctionalized Alkenes: A Boryl-Heck Reaction - Journal of the American Chemical Society (ACS Publications)

Abstract

We
report the first example of a boryl-Heck reaction using an
electrophilic boron reagent. This palladium-catalyzed process allows for
the conversion of terminal alkenes to trans-alkenyl boronic esters using commercially available catecholchloroborane (catBCl). In situ transesterification allows for rapid access to a variety of boronic esters, amides, and other alkenyl boron adducts.